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Evolutionary Coupling Analysis

Predicted and experimental contacts

Interactive contact map

Secondary structure from ECs

Known pdb structures

pdb chain
3j5l 1

EC score distribution and threshold

Top ECs

Rank Residue 1 Amino acid 1 Residue 2 Amino acid 2 EC score
1 18 G 42 V 1.69
2 19 H 49 Y 1.32
3 35 E 48 I 1.27
4 12 V 52 A 1.01
5 15 A 45 Q 0.92
6 37 K 46 H 0.88
7 19 H 52 A 0.85
8 35 E 50 K 0.85
9 8 K 22 T 0.84
10 37 K 48 I 0.84
11 16 G 40 D 0.77
12 13 S 40 D 0.71
13 21 Y 38 K 0.67
14 30 K 36 L 0.67
15 14 S 50 K 0.63
16 43 V 47 V 0.62
17 8 K 24 T 0.59
18 39 F 44 R 0.59
19 30 K 34 L 0.59
20 12 V 19 H 0.56
21 16 G 43 V 0.56
22 7 E 27 K 0.54
23 25 K 51 E 0.54
24 6 R 27 K 0.53
25 13 S 49 Y 0.48
26 11 L 23 T 0.48
27 37 K 45 Q 0.46
28 6 R 30 K 0.43
29 20 F 49 Y 0.43

Alignment robustness analysis

First most common residue correlation

Second most common residue correlation

Robustness